Synthesis and antiaggregative activity of derivatives of 3-aminopiperidine-2, 6-diones and 3-aminopyrrolidine-2, 5-diones

AA Krys' ko, VM Kabanov, TA Kabanova…

Index: Krys'ko; Kabanov; Kabanova; Belikova; Mazepa Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 6 p. 304 - 306

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Abstract

The search for new antithrombic and antiaggregative agents possessing high activity and low toxicity is a currently important task of pharmaceutical chemistry [1]. A large number of potential antiaggregants have been described in the literature by now, which can be divided into several groups according to the mechanism of their action. In one group, the mechanism is related to the arachidonic acid metabolism. Other groups are characterized by influence ...