Towards new neuroprotective agents: design and synthesis of 4H-thieno [2, 3-c] isoquinolin-5-one derivatives as potent PARP-1 inhibitors

R Pellicciari, E Camaioni, G Costantino, M Marinozzi…

Index: Farmaco, , vol. 58, # 9 p. 851 - 858

Full Text: HTML

Citation Number: 28

Abstract

... Volume 58, Issue 9, September 2003, Pages 851–858. ... a Dipartimento di Chimica e Tecnologia del Farmaco, Università degli Studi di Perugia, Via del Liceo 1, I-06123 Perugia, Italy; b Dipartimento di Farmacologia ... 40%) of the necrotic brain volume after ischemic insult (Fig. ...