Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

DP Smith, J Anderson, J Plante, AE Ashcroft…

Index: Smith, David P.; Anderson, Jon; Plante, Jeffrey; Ashcroft, Alison E.; Radford, Sheena E.; Wilson, Andrew J.; Parker, Martin J. Chemical Communications, 2008 , # 44 p. 5728 - 5730

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Citation Number: 9

Abstract

The separative and analytical power of ion mobility spectrometry-mass spectrometry combined with photo-induced cross-linking of site-specifically incorporated trifluoromethyldiazirine provides a powerful approach towards structural characterisation of amyloid fibrils.