Studies on non-thiazolidinedione antidiabetic agents. 2. Novel oxyiminoalkanoic acid derivatives as potent glucose and lipid lowering agents.

H Imoto, Y Sugiyama, H Kimura…

Index: Chemical and Pharmaceutical Bulletin, , vol. 51, # 2 p. 138 - 151

Full Text: HTML

Citation Number: 27

Abstract

... Takeda Chemical Industries, Ltd., Pharmaceutical Research Division; 2–17–85 Juso-Honmachi, Yodogawa-ku ... Chemistry The methods used to prepare the oxyiminoalkanoic acids are outlined in Chart 2 ... Chemical shifts are expressed as d (ppm) values for protons relative to the ...

Related Articles:

Studies on antidiabetic agents. 11. Novel thiazolidinedione derivatives as potent hypoglycemic and hypolipidemic agents

[Sohda; Mizuno; Momose; Ikeda; Fujita; Meguro Journal of Medicinal Chemistry, 1992 , vol. 35, # 14 p. 2617 - 2626]

Design and synthesis of N-[(4-methoxyphenoxy) carbonyl]-N-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl) ethoxy] phenyl] methyl] glycine [muraglitazar/BMS-298585], a novel …

[Devasthale, Pratik V.; Chen, Sean; Jeon, Yoon; Qu, Fucheng; Shao, Chunning; Wang, Wei; Zhang, Hao; Cap, Michael; Farrelly, Dennis; Golla, Rajasree; Grover, Gary; Harrity, Thomas; Ma, Zhengping; Moore, Lisa; Ren, Jimmy; Seethala, Ramakrishna; Cheng, Lin; Sleph, Paul; Sun, Wei; Tieman, Aaron; Wetterau, John R.; Doweyko, Arthur; Chandrasena, Gamini; Chang, Shu Y.; Humphreys, W. Griffith; Sasseville, Vito G.; Biller, Scott A.; Ryono, Denis E.; Selan, Fred; Hariharan, Narayanan; Cheng, Peter T. W. Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 2248 - 2250]

Design and synthesis of N-[(4-methoxyphenoxy) carbonyl]-N-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl) ethoxy] phenyl] methyl] glycine [muraglitazar/BMS-298585], a novel …

[Journal of Medicinal Chemistry, , vol. 48, # 6 p. 2248 - 2250]

Azole phenoxy hydroxyureas as selective and orally active inhibitors of 5-lipoxygenase

[Journal of Medicinal Chemistry, , vol. 39, # 1 p. 237 - 245]

Studies on antidiabetic agents. 11. Novel thiazolidinedione derivatives as potent hypoglycemic and hypolipidemic agents

[Journal of Medicinal Chemistry, , vol. 35, # 14 p. 2617 - 2626]

More Articles...