Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides

MH Norman, J Zhu, C Fotsch, Y Bo…

Index: Journal of Medicinal Chemistry, , vol. 50, # 15 p. 3497 - 3514

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Citation Number: 33

Abstract

... Journal of Medicinal Chemistry. ... 6 For example, early European folk medicine employed hot pepper extracts (hence capsaicin) to relieve toothaches, and native Americans were also known to have massaged chili pods onto their inflamed gums to ease dental pain. ...