Tetrahedron

NMR studies of n-methyl derivatives of the 2-azabicyclo-[2.2. 1] heptyl and-[2.2. 2] octyl ring systems; kinetic protonation in determination of Invertomer preferences

D Belkacemi, JR Malpass

Index: Belkacemi, Djaballah; Malpass, John R. Tetrahedron, 1993 , vol. 49, # 40 p. 9105 - 9116

Full Text: HTML

Citation Number: 16

Abstract

The title compounds were studied by 1H, 13C, and 15N NMR spectroscopy. Since inversion at nitrogen is rapid on the NMR time scale even at low temperatures, kinetic protonation was used to estimate invertomer ratios at ambient temperature. Invertomer preferences appear to be consistent with the operation of steric factors.