Steroids. LXXI. 1 Synthesis of 1-Dehydroprogesterone and 1-Dehydro-17-ethinyltestosterone

F Sondheimer, M Velasco…

Index: Sondheimer et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 192

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Citation Number: 18

Abstract

The recent discovery2 that 1-dehydrocortisone and 1-dehydrohydrocortisone possess medicinal properties superior to those of the parent hormones has focussed attention on the 1-dehydro derivatives of other steroidal hormones. I-Dehydrotestoster-I- dehydrodesoxycorticosterone a~ etate,~ 1-dehydro-17-hydroxypr~ gesterone~ and l- dehydro-17-hydroxydesoxycorticosterone acetate5 are all known compounds. The 1- ...