The Journal of Organic Chemistry

Dynamic kinetic resolutions catalyzed by a planar-chiral derivative of DMAP: enantioselective synthesis of protected α-amino acids from racemic azlactones

J Liang, JC Ruble, GC Fu

Index: Liang, Jack; Ruble, Craig; Fu, Gregory C. Journal of Organic Chemistry, 1998 , vol. 63, # 10 p. 3154 - 3155

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Citation Number: 143

Abstract

Due to the widespread occurrence of R-amino acids in biologically active compounds, the development of efficient methods for their enantioselective synthesis is a challenge of considerable practical importance. 1 To date, approaches that employ stoichiometric chiral auxiliaries have been the primary focus of attention, although several effective catalytic methods have also been reported, perhaps most notably the metal-catalyzed asymmetric ...

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