Chemical modification of ansamitocins. II. Synthesis of 3-epimaytansionoids via 3-maytansinones.

秋元浩， 河合昭悦， 橋本直人， 野村容朗

Index: Chemical and Pharmaceutical Bulletin, , vol. 32, # 7 p. 2565 - 2570

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Citation Number: 10

Abstract

... via 3-Maytansinones HIROSHI AKIMOTO,* AKIYOSHI KAWAI, NAOTO HASHIMOTO, and HIROAKI NOMURA Chemistry Laboratories, Central ... activity and relatively Severe side effects of maytansine“ have prompted us to conduct chemical modification studies ... Page 2. 2566 Vol. ...