Facile Access to 3??Acylindoles through Palladium??Catalyzed Addition of Indoles to Nitriles: The One??Pot Synthesis of Indenoindolones

Y Ma, J You, F Song

Index: Ma, Yuanhong; You, Jingsong; Song, Feijie Chemistry - A European Journal, 2013 , vol. 19, # 4 p. 1189 - 1193

Full Text: HTML

Citation Number: 56

Abstract

Considerable progress has been made over the past decade in transition-metal-catalyzed CÀH bond functionalization of arenes and heteroarenes.[1] The pioneering work of Larock showed that palladium could catalyze the addition reaction of electron-rich arenes with polar nitriles to afford arylketones.[2] This work was subsequently followed up by a number of reports including the addition of arylboronic acids,[3] arylhalides,[4] and benzoic acids [5] ...