1H and 13C NMR study of 2??aminothiazole urinary tract carcinogens

RM Davidson, JR Rice, VM Lakshmi…

Index: Davidson, R. M.; Rice, J. R.; Lakshmi, V. M.; Zenser, T. V.; Davis, B. B. Magnetic Resonance in Chemistry, 1988 , vol. 26, p. 482 - 487

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Citation Number: 5

Abstract

Abstract Using 1 H and 13 C NMR, 13 C-labelled modifications of 2-amino-4-(5-nitro-2-furyl) thiazole (ANFT) and its N-formyl analogue N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide (FANFT), as well as the 5-(S)-substituted glutathione and N-acetylcysteine conjugates of prostaglandin H synthase-catalyzed peroxidative metabolism of ANFT were studied. 1 H and 13 C NMR chemical shifts, heteronuclear coupling constants, spin–lattice relaxation times ...