Pronounced rate enhancements in condensation reactions attributed to the fluorous tag in modified Mukaiyama reagents

M Matsugi, S Nakamura, Y Kunda, Y Sugiyama…

Index: Matsugi, Masato; Nakamura, Shuichi; Kunda, Yoko; Sugiyama, Yuya; Shioiri, Takayuki Tetrahedron Letters, 2010 , vol. 51, # 1 p. 133 - 135

Full Text: HTML

Citation Number: 11

Abstract

The observed rate enhancement for the condensation reaction between 2-phenyl benzoic acid and isopropanol mediated by fluorous Mukaiyama reagents is described. It is shown that Mukaiyama reagents bearing a fluorous tag increase the reaction rate considerably when compared to their non-fluorous tagged counterpart. Furthermore, it is observed that the longer the fluorous chain, the higher the activity of the Mukaiyama reagent.

Related Articles:

RuH 2 (CO)(PPh 3) 3-catalyzed arylation of aromatic esters using arylboronates via C–H bond cleavages

[Kitazawa, Kentaroh; Kotani, Masashi; Kochi, Takuya; Langeloth, Michael; Kakiuchi, Fumitoshi Journal of Organometallic Chemistry, 2010 , vol. 695, # 8 p. 1163 - 1167]

Organische Photochemie, XIV. Photoreaktionen sulfinylsubstituierter Carbonsäure??, Thiocarbonsäure??und Selenocarbonsäurederivate in Lösung; lichtinduzierte …

[Luedersdorf,R. et al. Justus Liebigs Annalen der Chemie, 1977 , p. 1992 - 2017]

More Articles...