Tetrahedron

Copper-catalyzed direct cross coupling of 1, 3, 4-oxadiazoles with trans-β-halostyrenes: synthesis of 2-E-vinyl 1, 3, 4-oxadiazoles

B Das, GC Reddy, P Balasubramanyam, N Salvanna

Index: Das, Biswanath; Reddy, Gandolla Chinna; Balasubramanyam, Penagaluri; Salvanna Tetrahedron, 2012 , vol. 68, # 1 p. 300 - 305

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Citation Number: 14

Abstract

The widespread application of heteroarenes in medicinal chemistry and in material science has driven the development of new synthetic strategies to prepare appropriately substituted heterocyclic cores. Metal-catalyzed direct functionalization of C–H bond of heteroarenes is great importance in recent organic synthesis to generate molecular complexity. 1, 1a, 1b, 1c, 1d and 1e In fact, the transformation of C–H to C–C bond in the presence of a metal catalyst is a highly ...

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