Highly Efficient Synthesis of 5??Substituted 1H??Tetrazoles Catalyzed by Cu–Zn Alloy Nanopowder, Conversion into 1, 5??and 2, 5??Disubstituted Tetrazoles, and …

G Aridoss, KK Laali

Index: Aridoss, Gopalakrishnan; Laali, Kenneth K. European Journal of Organic Chemistry, 2011 , # 31 p. 6343 - 6355

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Citation Number: 38

Abstract

Abstract A series of 5-substituted 1H-tetrazoles were synthesized through [3+ 2] cycloaddition reactions between nitriles RCN and NaN 3 in the presence of Cu–Zn alloy nanopowder as catalyst. The 1, 5-dibutyl, 1-butyl-5-hexyl, 2, 5-dibutyl, and 2-butyl-5-hexyl derivatives were then used as building blocks to synthesize several novel tetrazolium ionic liquids (ILs) with EtSO 4–, OTf–, and NTf 2–counterions. Whereas alkylation of the 2, 5- ...