Trichloroisocyanuric acid-catalyzed one-pot synthesis of 2, 4, 5-trisubstituted imidazoles

SF Hojati, SA Nezhadhoseiny, Z Beykzadeh

Index: Hojati, Seyedeh Fatemeh; Nezhadhoseiny, Seyede Atefe; Beykzadeh, Zahra Monatshefte fur Chemie, 2013 , vol. 144, # 3 p. 387 - 390

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Citation Number: 11

Abstract

Abstract Trichloroisocyanuric acid was found to be a highly efficient homogeneous catalyst for synthesis of imidazoles via one-pot, three-component condensation of aldehydes with benzil and ammonium acetate. The valuable advantages of this method are high yields of products, easy work-up and purification procedure, and use of a commercially available, inexpensive, and non-volatile catalyst. Graphical abstract