Organic letters

Alkynyltrifluoroborates as versatile tools in organic synthesis: A new route to spiroketals

J Doubský, L Streinz, D Šaman, J Zednik…

Index: Doubsky, Jan; Streinz, Ludvik; Leseticky, Ladislav; Koutek, Bohumir Synlett, 2003 , # 7 p. 937 - 942

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Citation Number: 27

Abstract

A simple and efficient two-step approach to spiroketals is described. Key steps include the preparation of functionalized hydroxyl α-alkynones by ring-opening reactions of lactones with lithium alkynyltrifluoroborates followed by a palladium-catalyzed hydrogenation/

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