Nickel, manganese, cobalt, and iron-catalyzed deprotonative arene dimerization

T Truong, J Alvarado, LD Tran, O Daugulis

Index: Truong, Thanh; Alvarado, Joseph; Tran, Ly Dieu; Daugulis, Olafs Organic Letters, 2010 , vol. 12, # 6 p. 1200 - 1203

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Citation Number: 76

Abstract

A number of first-row transition metal salts catalyze deprotonative dimerization of acidic arenes. Under the atmosphere of oxygen, nickel, manganese, cobalt, and iron chlorides have been shown to dimerize five-and six-membered ring heterocycles as well as electron- poor arenes. Both tetramethylpiperidide and dicyclohexylamide bases can be employed; however, the former afford slightly higher yields.