Medicinal chemistry research

Pharmacological characteristics of some 3-salicylidenehydrazono-2-indolinone coordination compounds

SS Konstantinović, VS Cakić

Index: Konstantinovic, Sandra S.; Cakic, Vanja S. Medicinal Chemistry Research, 2010 , vol. 19, # 8 p. 771 - 781

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Citation Number: 5

Abstract

Abstract 3-Salicylidenehydrazono-2-indolinone (SHI) complexes with Co (II), Ni (II), Cu (II), Zn (II), and Pd (II) were synthesized. All compounds were evaluated for their antimicrobial activity against seven pathogenic bacteria and four fungi. The compounds also have been screened for anti-inflammatory activity. The complexes have better antimicrobial and anti- inflammatory than ligand itself. The in vitro antiamoebic activity was evaluated against the ...