Tetrahedron Letters

Radical aromatic substitution with benzene chromiumtricarbonyl

JH Byers, NR Neale, JB Alexander, SP Gangemi

Index: Byers, Jeffrey H.; Neale, Nathan R.; Bradford Alexander; Gangemi, Stephen P. Tetrahedron Letters, 2007 , vol. 48, # 44 p. 7903 - 7905

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Citation Number: 3

Abstract

Radical aromatic substitution of tert-butyl groups for hydrogen on simple arene chromiumtricarbonyl complexes was accomplished. Preexisting tert-butyl groups and methoxy groups directed incoming radicals primarily to the meta-position, and methoxy groups diminished the rate of substitution by roughly tenfold.