Tetrahedron Letters

A novel TMSI-mediated synthesis of Hantzsch 1, 4-dihydropyridines at ambient temperature

G Sabitha, GSKK Reddy, CS Reddy, JS Yadav

Index: Sabitha, Gowravaram; Reddy, G.S. Kiran Kumar; Reddy, Ch. Srinivas; Yadav Tetrahedron Letters, 2003 , vol. 44, # 21 p. 4129 - 4131

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Citation Number: 284

Abstract

The synthesis of various substituted Hantzsch 1, 4-dihydropyridines has been achieved using the classical Hantzsch procedure and modified Hantzsch conditions for the first time at room temperature in the presence of iodotrimethylsilane (TMSI) generated in situ in CH3CN, in excellent yields.

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