Pd (II)-catalyzed ortho arylation of 6-arylpurines with aryl iodides via purine-directed C− H activation: A new strategy for modification of 6-arylpurine derivatives

HM Guo, LL Jiang, HY Niu, WH Rao, L Liang…

Index: Guo, Hai-Ming; Xin, Peng-Yang; Niu, Hong-Ying; Wang, Dong-Chao; Jiang, Yi; Qu, Gui-Rong Green Chemistry, 2010 , vol. 12, # 12 p. 2131 - 2134

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Citation Number: 37

Abstract

Purine is utilized as a new directing group for the Pd-catalyzed monoarylation of 6- arylpurines with simple aryl iodides via C− H bond activation in good yields, providing a complementary tool for the modification of 6-arylpurines (nucleosides). Most importantly,