Reactive nitrogen oxygen species metabolize N-acetylbenzidine

VM Lakshmi, FF Hsu, BB Davis…

Index: Lakshmi; Fong Fu Hsu; Davis; Zenser Chemical Research in Toxicology, 2001 , vol. 14, # 3 p. 312 - 318

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Citation Number: 6

Abstract

A close association has been reported for certain types of cancers influenced by aromatic amines and infection/inflammation. Reactive nitric oxygen species (RNOS), components of the inflammatory response, are bactericidal and tumoricidal, and contribute to the deleterious effects attributed to inflammation on normal tissues. This study assessed the possible transformation of the aromatic amine N-acetylbenzidine (ABZ) by RNOS. RNOS ...