The scope and mechanism of a novel synthesis of 3, 4-fused isoxazoles

KJ Duffy, G Tennant

Index: Duffy, Kevin J.; Tennant, George Journal of the Chemical Society, Chemical Communications, 1995 , # 23 p. 2457 - 2460

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Citation Number: 9

Abstract

Thermal cyclisation of 2-nitrophenyl-and 3-nitrohetaryl-ethanoate derivatives in xylene is facilitated indirectly by 5 Å molecular sieves affording an efficient general method for the construction of synthetically useful 3, 4-fused isoxazoles; evidence for the mechanism of these novel heterocyclisation reactions is presented.