Spiroaminobarbituric Acids. I1

JA Stanfield, PM Daugherty

Index: Stanfield; Daugherty Journal of the American Chemical Society, 1959 , vol. 81, p. 5167,5169

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Citation Number: 5

Abstract

The synthesis of several nitrogen-substituted alkyl, substituted alkyl and aryl derivatives of spiropiperidine-4', 5-barbituric acid is reported. It has been observed that the stability of the spiro-l'-methylpiperidine-4', 5-barbituric acid is of the same order of magnitude as barbital and is somewhat more stable than the spirotetrahydropyran-or the spirocyclopentanebarbituric acids. The pharmacological examinations of the 1'-phenyl- ...