Metal-free aerobic oxidation of benzazole derivatives

A Dos Santos, L El Kaïm, L Grimaud

Index: Dos Santos, Aurelie; El Kaim, Laurent; Grimaud, Laurence Organic and Biomolecular Chemistry, 2013 , vol. 11, # 20 p. 3282 - 3287

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Citation Number: 8

Abstract

Similar transformations were also reported with benzothiazoles, benzoxazoles as well as their related non-fused heterocycles. 5 Oxygen may be used in place of these toxic reagents but a metal salt such as CoCl 2 6 or RuCl 3 7 was added for the conversion into ketones. While working on alkylations of 2-benzylbenzimidazole derivatives, the ketone was frequently obtained as a side-product. To control this process, we decided to examine further the aerobic oxidation ...

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