Journal of fluorine chemistry

Synthesis and bioactivity of novel (3-chloro-5-(trifluoromethyl) pyridin-2-yloxy) phenyl containing acrylate and acrylonitrile derivatives

CR Yu, LH Xu, S Tu, ZN Li, B Li

Index: Yu, Chun-Rui; Xu, Long-He; Tu, Song; Li, Zhi-Nian; Li, Bin Journal of Fluorine Chemistry, 2006 , vol. 127, # 12 p. 1540 - 1546

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Citation Number: 10

Abstract

Fifteen novel (3-chloro-5-(trifluoromethyl) pyridin-2-yloxy) phenyl containing Baylis-Hillman adduct derivatives were designed and synthesized. Evaluation of their biological activities showed that methyl 2-((3-(3-chloro-5-(trifluoromethyl) pyridin-2-yloxy) phenoxy)(phenyl) methyl) acrylate (2g) exhibited efficient broad-spectrum fungicidal activity, with 100% control of wheat powdery mildew and cucumber downy mildew and 98% control of cucumber ...