Artificial redox enzymes. 1. Synthetic strategies

…, H Ye, TR Boehlow, VT D'Souza

Index: Rong, Ding; Ye, Hongping; Boehlow, Todd R.; D'Souza, Valerian T. Journal of Organic Chemistry, 1992 , vol. 57, # 1 p. 163 - 167

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Citation Number: 19

Abstract

Organic models of flavoenzymes consist of a binding site covalently attached to a flavin derivative acting as the catalytic site. The earlier reported synthesis of such a model using a- cyclodextrin as the binding site proved to be difficult to reproduce with P-cyclodextrin. The synthetic strategy involved attaching a fully constructed riboflavin onto a cyclodextrin by a nucleophilic reaction. Riboflavin was found to decompose under the reaction conditions. A ...