Synthesis and cyclization reactions of 2??amino??3??[(methoxy??carbonyl) methylsulfonyl] pyrroles and thiophene

CE Stephens, JW Sowell

Index: Stephens, Chad E.; Walter Sowell Sr. Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 4 p. 933 - 938

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Citation Number: 3

Abstract

Abstract The title aminopyrroles and thiophene have been prepared by condensation of methyl (cyanomethyl-sulfonyl) acetate with various α-amino ketones or 2- mercaptoacetaldehyde, respectively. Subsequent cyclization of these compounds by reaction between the amine and activated methylene has led to various ester-substituted thiazine-and thiadiazine-based bicyclic derivatives. In addition, cyclization of the title ...