Metalloenzyme Models. Divalent Metal Ion Catalyzed Hydrolysis of p-Nitrophenyl Picolinate in the Presence of Imidazoles and Pyridines Having Hydroxyl Groups in …

K Ogino, K Shindo, T Minami, W Tagaki…

Index: Ogino, Kenji; Shindo, Katsuhiko; Minami, Tooru; Tagaki, Waichiro; Eiki, Toshio Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 4 p. 1101 - 1106

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Citation Number: 32

Abstract

Rate constants for hydrolysis of p-nitrophenyl picolinate at 25° C in the pH range 6.5–8.5 were measured in the absence and presence of divalent metal ions (Ni (II), Zn (II), Co (II), Ca, Mg) and substituted imidazoles or pyridines as ligands having alcoholic hydroxyl groups in their side chains. In the presence of either metal ion or ligand, the rate is slow and the pseudo-first-order rate constant (k obsd) increases linearly in a first-order manner with ...