Ruthenium-Catalyzed Selective α, β-Deuteration of Bioactive Amines

…, S Imm, H Neumann, J Atzrodt, V Derdau…

Index: Derdau, Volker; Atzrodt, Jens; Zimmermann, Jochen; Kroll, Carsten; Brueckner, Francois Chemistry - A European Journal, 2009 , vol. 15, # 40 p. 10397 - 10404

Full Text: HTML

Citation Number: 31

Abstract

A novel and convenient protocol for the catalytic hydrogen–deuterium exchange of biologically active tertiary amines utilizing the borrowing hydrogen methodology has been developed. In the presence of the readily available Shvo catalyst, excellent ...