Triple condensation of aryl methyl ketones catalyzed by amine and trifluoroacetic acid: straightforward access to 1, 3, 5-triarylbenzenes under mild conditions
SL Zhang, ZF Xue, YR Gao, S Mao, YQ Wang
Index: Zhang, Shao-Liang; Xue, Zhao-Feng; Gao, Ya-Ru; Mao, Shuai; Wang, Yong-Qiang Tetrahedron Letters, 2012 , vol. 53, # 19 p. 2436 - 2439
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Citation Number: 9
Abstract
An efficient triple condensation reaction of aryl methyl ketones catalyzed by ethylenediamine and trifluoroacetic acid was reported. A broad scope of 1, 3, 5-triarylbenzenes was obtained in good to excellent yields. The reaction provides a novel and practical approach to access organic materials of polycyclic aromatic hydrocarbons under mild conditions.
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