Base directed palladium catalysed Heck arylation of acrolein diethyl acetal in water

W Al-Maksoud, S Menuel, M Jahjah, E Monflier…

Index: Al-Maksoud, Walid; Menuel, Stephane; Jahjah, Mohamad; Monflier, Eric; Pinel, Catherine; Djakovitch, Laurent Applied Catalysis A: General, 2014 , vol. 469, p. 250 - 258

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Citation Number: 4

Abstract

Abstract The selective Heck arylation of acrolein diethyl acetal catalysed by [Pd (NH 3) 4] Cl 2 in the presence of RAME-β-CD in water as solvent is described. Depending on the base (ie NaOAc or HN (i-Pr) 2) good to high selectivity's towards, respectively, the cinnamaldehydes 2 or the 3-arylpropionic esters 1 were achieved. The results support that depending on the base different palladium intermediate complexes are formed. Using ...