Synthesis of some polyimidazole ligands related to zinc enzymes

…, JT Hunt, R Smiley, T Tarnowski

Index: Breslow, Ronald; Hunt, John T.; Smiley, Richard; Tarnowski, Thomas Journal of the American Chemical Society, 1983 , vol. 105, # 16 p. 5337 - 5342

Full Text: HTML

Citation Number: 83

Abstract

Abstract: Methods have been developed for the synthesis of new ligands bearing imidazole groups. Tris (imidazoly1) ethane and tris (imidazo1yl) butane derivatives have a more expanded geometry than the known tris (imidazolyl) carbinols, leading in at least one case to better binding to metals. Ligands carrying 2-phenylimidazole rings show altered properties because of the bulky phenyl substituent. Methods have been devised to ...