Organic letters

Fusing triazoles: toward extending aromaticity

M Juríček, K Stout, PHJ Kouwer, AE Rowan

Index: Juricek, Michal; Stout, Kathleen; Kouwer, Paul H. J.; Rowan, Alan E. Organic Letters, 2011 , vol. 13, # 13 p. 3494 - 3497

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Citation Number: 29

Abstract

A novel method to extend aromaticity by one benzene and two triazole rings was developed and optimized. This two-step route employs the copper-catalyzed azide–haloalkyne cycloaddition reaction of an ortho-bis (iodoacetylene) system and the subsequent intramolecular homocoupling fusion of the neighboring iodotriazoles, a process in which an additional benzene ring is formed. This versatile methodology allows one to extend the ...

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