Piperazinylalkyl prodrugs of naproxen improve in vitro skin permeation

J Rautio, T Nevalainen, H Taipale…

Index: European Journal of Pharmaceutical Sciences, , vol. 11, # 2 p. 157 - 163

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Citation Number: 67

Abstract

... European Journal of Pharmaceutical Sciences. ... of improving topical absorption have been performed, such as the prodrug approach with the aim of changing pharmaceutical and/or ... 1 H NMR (CDCl 3 , 400 MHz) d 7.71–7.10 (6H, m, aromatic), 4.09 (2H, dt, OCH 2 CH 2 , J=6.5 Hz ...