Tetrahedron letters

An anionic condensation and fragmentation approach to substituted 3-pyrrolines

GM Weeresakare, Q Xu, JD Rainier

Index: Weeresakare, G.Mahika; Xu, Qing; Rainier, Jon D. Tetrahedron Letters, 2002 , vol. 43, # 49 p. 8913 - 8915

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Citation Number: 8

Abstract

We have identified an anionic condensation and fragmentation sequence from the coupling of 7-azabicyclo [2.2. 1] heptenones with aldehydes. This reaction leads to the stereoselective formation of disubstituted 3-pyrrolines as are present in a wide array of bioactive molecules.