Farmaco

4-Substituted 1-methyl-1H-indazoles with analgesic, antiinflammatory and antipyretic activities

…, G Menozzi, P Fossa, P Schenone, E Lampa, C Parrillo…

Index: Mosti; Menozzi; Fossa; Schenone; Lampa; Parrillo; D'Amico; Rossi Farmaco, 1992 , vol. 47, # 5 p. 567 - 584

Full Text: HTML

Citation Number: 39

Abstract

SUMMARY-The synthesis 0f [(1-meth yl-IH-indazol-4-yl) oxy] acetic acid 4, I-meth yl-IH- indazole4-acelic acid 9, 2-(1-methyl-IH-indazoL4-yl) propanoic acid 15 and [[(1, 5, 6, 7- tetrahydr0» 1-methyI-4H-indazol-4-ylidene) amino] oxyjacetic acid 16, as well as ofamides and esters derivedfrom 4 and 9, startingfrom 1, 5, 6, 7-tetrahydro-1-methyl-4H-indazol-4-one is described. Some of the above compounds showed weak antiinflammatory, analgesic, ...