Alternate syntheses of PRODAN and ACRYLODAN

SS Silvonek, CB Giller, CJ Abelt

Index: Silvonek, Steven S.; Giller, Carl B.; Abelt, Christopher J. Organic Preparations and Procedures International, 2005 , vol. 37, # 6 p. 589 - 594

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Citation Number: 7

Abstract

Fanis in 1979 as a fluorescent probe of micropolarity.'The prodan moiety was attached to thiols and amines in proteins using acrylodan [6-acryloyl-2-(dimethylamino) naphthalene, 12]. 2* 3 The covalently bound chromophore is a fluorescent molecular sensor of the labeled We have been interested in preparing derivatives of prodan and acrylodan to understand the nature of the emissive intramolecular charge-transfer state. The literature synthesis of ...