Canadian journal of chemistry

Directed ortho metalation reactions. Convergent synthesis of" angular" anthracyclinones ochromycinone and X-14881 C

K Katsuura, V Snieckus

Index: Katsuura, K.; Snieckus, V. Canadian Journal of Chemistry, 1987 , vol. 65, p. 124 - 130

Full Text: HTML

Citation Number: 42

Abstract

Convergent syntheses of the benz [a] anthraquinone natural products X-14881 C (2 c) and ochromycinone (2 d) have been achieved using aromatic directed metalation strategies. Key steps involve (a) the condensations of dilithiated cis-tetralol (13 a) with the aldehydo o- anisamide 14 and of methoxymethyl protected aldehyde 17 b with lithiated o-anisamide (18) to give, after acid-catalyzed cyclization, the phthalide 16, and (b) the regiospeciflc ...

Related Articles:

Efficient Access to Methyl-1-hydroxy-2-naphthoates and Heterocyclic Analogues

[Cui, Li-Qian; Dong, Zhi-Lei; Liu, Kai; Zhang, Chi Organic Letters, 2011 , vol. 13, # 24 p. 6488 - 6491]

Rhodium-Catalyzed, Enantioselective Hydroacylation of ortho-Allylbenzaldehydes

[Beletskiy, Evgeny V.; Sudheer; Douglas, Christopher J. Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 5884 - 5893]

Efficient Access to Methyl-1-hydroxy-2-naphthoates and Heterocyclic Analogues

[Cui, Li-Qian; Dong, Zhi-Lei; Liu, Kai; Zhang, Chi Organic Letters, 2011 , vol. 13, # 24 p. 6488 - 6491]

Efficient Access to Methyl-1-hydroxy-2-naphthoates and Heterocyclic Analogues

[Cui, Li-Qian; Dong, Zhi-Lei; Liu, Kai; Zhang, Chi Organic Letters, 2011 , vol. 13, # 24 p. 6488 - 6491]

Directed ortho metalation reactions. Synthesis of the naturally-occurring benz [a] anthraquinones X-14881 C and ochromycinone

[Katsuura, K.; Snieckus, V. Tetrahedron Letters, 1985 , vol. 26, # 1 p. 9 - 12]

More Articles...