Novel syntheses of chiral β-and γ-amino acid derivatives utilizing N-protected (aminoacyl) benzotriazoles from aspartic and glutamic acids

AR Katritzky, H Tao, R Jiang, K Suzuki…

Index: Katritzky, Alan R.; Suzuki, Kazuyuki; Singh, Sandeep K. Croatica Chemica Acta, 2004 , vol. 77, # 1-2 p. 175 - 178

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Citation Number: 26

Abstract

Friedel-Crafts reactions of N-protected (α-aminoacyl) benzotriazoles with hetero-and benzenoid-aromatics give α-amino ketones that can be reduced by either triethyl silane or sodium borohydride to form the corresponding β-and γ-amino acid derivatives. The