Synthesis and pharmacological activity of metabolites of the 5-HT 4 receptor antagonist SB-207266

M Fedouloff, F Hossner, M Voyle, J Ranson…

Index: Fedouloff, Michael; Hossner, Frank; Voyle, Martyn; Ranson, Jennie; Powles, Jenifer; Riley, Graham; Sanger, Gareth Bioorganic and Medicinal Chemistry, 2001 , vol. 9, # 8 p. 2119 - 2128

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Citation Number: 20

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Three metabolites of N-[(1-butyl-4-piperidinyl)methyl]-3,4-dihydro-2H-[1,3]-oxazino[3,2_a]indole-10-carboxamide (SB-207266) (1) were synthesised and their pharmacological activity determined. ... Three metabolites of N-[(1-butyl-4-piperidinyl)methyl]-3,4-dihydro-2H-[1,3]-oxazino[3,2-a]indole-10- ...