One-pot Synthesis of 2-Substituted Benzoxazoles Promoted by Copper Acetate Monohydrate

GF Chen, HD Shen, LY Zhang, HY Li…

Index: Chen, Guo-Feng; Shen, Hai-Dong; Zhang, Li-Yan; Li, Hong-Yang; Lan, Rui-Jia; Chen, Bao-Hua; Li, Ji-Tai; Hu, Qing-Hui Letters in Organic Chemistry, 2014 , vol. 11, # 3 p. 180 - 187

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Abstract

An efficient synthesis of 2-substituted benzoxazoles via copper acetate monohydrate oxidative coupling of aldehydes with o-aminophenol is described. This synthetic strategy has some advantages as simple procedure, inexpensive and easily available catalyst, and facile isolation of the products in moderate to good yields.

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