Aggregation behaviour of peptide–polymer conjugates containing linear peptide backbones and multiple polymer side chains prepared by nitroxide-mediated radical …

M Möller, C Hentschel, L Chi, A Studer

Index: Moeller, Michael; Hentschel, Carsten; Chi, Lifeng; Studer, Armido Organic and Biomolecular Chemistry, 2011 , vol. 9, # 7 p. 2403 - 2412

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Citation Number: 13

Abstract

A series of peptides with an alternating sequence of alkoxyamine conjugated lysine and glycine residues were synthesized by classical solution phase peptide coupling. The resulting peptides containing up to eight alkoxyamine moieties were used as initiators in nitroxide-mediated polymerization (NMP) to obtain peptide–polymer conjugates with well defined linear peptide backbones and a defined number of polymeric side chains. ...