Structure− activity study of new inhibitors of human betaine-homocysteine S-methyltransferase

…, P Kabeleová, M Šanda, M Kožíšek…

Index: McHintosh, John M.; Pillon, Lilianna Z.; Acquaah, Samuel O.; Green, James R.; White, Graham S. Canadian Journal of Chemistry, 1983 , vol. 61, p. 2016 - 2021

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Citation Number: 9

Abstract

... 1 were designed using the scaffold of the previously published potent inhibitor 1 to investigate the role of the number and position of sulfur atom(s) in the ... rt; (b) (ClCH 2 CH 2 ) 2 O. (ii) NaI, Me 2 CO, 65 °C. (iii) Methyl acrylate, Zn(Cu), EtOH-H 2 O, ultrasound, rt. (iv) 3 M HCl, reflux ...

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