Indium-mediated one-pot, three-component synthesis of homoallyl alcohol esters without catalysts and dehydrants

Z Du, Y Li, F Wang, W Zhou, JX Wang

Index: Du, Zhengyin; Li, Yanchun; Wang, Fen; Zhou, Wanwei; Wang, Jin-Xian Tetrahedron Letters, 2010 , vol. 51, # 13 p. 1745 - 1747

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Citation Number: 6

Abstract

Indium-mediated one-pot esterification reaction of acyl chlorides or anhydride by using in situ-prepared homoallyl alcohols from aromatic aldehydes and allyl bromide proceeded smoothly to afford the corresponding homoallyl alcohol esters in high yields within about 1h, which provided a simple and efficient protocol for the simultaneous allylation and esterification of aldehydes without other catalysts and dehydrants.