Ribozymomimetic chemical synthesis of peptide bond using phosphorous acid/oxirane mediators

S Bayryamov, D Danalev, N Vassilev

Index: Bayryamov; Danalev; Vassilev Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 2 p. 338 - 344

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Citation Number: 4

Abstract

Abstract A model system is created that mimics natural ribosome as well as the way of ribozyme action. It uses oxirane analogue as condensation reagent and H3PO3 as activator for the carboxyl group and as protecting reagent for the NH2 function. In order to

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