Novel inhibitors of prolyl 4-hydroxylase. 5. The intriguing structure-activity relationships seen with 2, 2'-bipyridine and its 5, 5'-dicarboxylic acid derivatives
NJ Hales, JF Beattie
Index: Journal of Medicinal Chemistry, , vol. 36, # 24 p. 3853 - 3858
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Citation Number: 37
Abstract
... Geometric mean of n determinations. Aldrich Chemical Co. d C, 51.3; H, 4.2; N, 10.6; HzO, 7.5. ... 2,l'-Bipyridine (3) (1Cg~ = 34 pM) clearly falls squarely into this class of inhibitor whereas Page 4. 3856 Journal of Medicinal Chemistry, 1993, Vol. 36, No. 24 ...
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