Reactions of heterocumulenes with organometallic reagents: XVII. One-pot synthesis of alkoxy and (alkylsulfanyl)-substituted pyrroles and 2, 3-dihydropyridines from …

NA Nedolya, L Brandsma, OA Tarasova…

Index: Nedolya; Brandsma; Tarasova; Albanov; Trofimov Russian Journal of Organic Chemistry, 2011 , vol. 47, # 5 p. 659 - 677

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Citation Number: 16

Abstract

Abstract A fundamentally new approach was developed to designing pyrrole and dihydropyridine rings from available allenes and isothiocyanates involving a single preparative stage. Applying the reaction of lithiated alkoxyallenes with aliphatic isothiocyanates we have synthesized previously unknown 1-alkyl (cycloalkyl) pyrroles and 2, 3-dihydropyridines with rare alkoxy-and alkylsulfanyl substituents. It was proved that the ...

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