Diastereo??and Enantioselective Intramolecular C (sp3) H Arylation for the Synthesis of Fused Cyclopentanes

N Martin, C Pierre, M Davi, R Jazzar…

Index: Martin, Nicolas; Pierre, Cathleen; Davi, Michail; Jazzar, Rodolphe; Baudoin, Olivier Chemistry - A European Journal, 2012 , vol. 18, # 15 p. 4480 - 4484

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Citation Number: 68

Abstract

Transition-metal catalysis has recently emerged as a powerful tool to functionalize otherwise unreactive CACHTUNGTRENNUNG (sp2) ÀH and CACHTUNGTRENNUNG (sp3) ÀH bonds.[1–2] In this context, recent research from our group [3] and others [4] has focused on the intramolecular arylation of unactivated CACHTUNGTRENNUNG (sp3) ÀH bonds to aryl halides under palladium (0) catalysis, giving rise to original polycylic molecules.[5] To date ...