2 (5-Nitro-2-thienyl) cinchoninic acids

I Lalezari, F Ghabgharan…

Index: Lalezari,I. et al. Journal of Medicinal Chemistry, 1971 , vol. 14, p. 465

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Citation Number: 5

Abstract

24 2-Thieny1) cinchoninic Acids.-A mixture of 0.02-mole quantities of an appropriate isat, in and 2-acetylthiophene in 15 ml of aq 2OYc KOH and 15 ml of EtOH was heated under reflux for 12 hr. The reaction mixt was cooled and acidified with dil HCl and the resulting yellow ppt was removed by filtration and crystd from AcOH (See Table I).